Exciting news for patients! Xiidra has the BEST* insurance coverage for any branded dry eye prescription product across Commercial and Medicare prescription plans!
Get to the Root of Your Symptoms
Not all eye drops work the same way.
Xiidra was made to target inflammation—so it can get to the root of your chronic dry eye symptoms.
If your symptoms keep coming back, it could be a sign you need something that works differently.
*Based on MMIT data from February 2025. Up to 94% of commercial and 70% of Medicare Part D patients may be covered.
Why Xiidra?
The Whole Picture
Xiidra treats both the signs and symptoms of dry eye disease.
Works Fast
Xiidra is the only nonsteroid anti-inflammatory prescription that can start to deliver lasting dry eye symptom relief in just 2 weeks, with continued twice-daily use.†
Gets to the Root
Unlike over-the-counter eye drops‡ (that just pause dry eye symptoms), Xiidra works by targeting a source of inflammation.
Commonly Used
As many as 1,500,000 people§ have been prescribed Xiidra.
†Xiidra may provide lasting symptom relief for some patients with continued twice-daily use. In clinical studies, Xiidra reduced symptoms of eye dryness at 2 weeks in 2 out of 4 studies, with improvements observed at 6 and 12 weeks in all 4 studies.
‡Over-the-counter eye drops=artificial tears.
§Based on an analysis of IQVIA LRx claims data from July 2016 to January 2024.
Xiidra May Provide Lasting Dry Eye Symptom Relief—in as Little as 2 Weeks†
- Xiidra has been studied in more than 1000 patients with dry eye in 4 separate 12-week clinical studies.
- On average at 12 weeks, some Xiidra patients were seen to have reduced symptoms of eye dryness in all 4 studies.
Ask your eye doctor if Xiidra is right for you.
In clinical studies, Xiidra was shown to, on average:
In a real-world study, patients who wore contact lenses and took Xiidra:
†Xiidra may provide lasting symptom relief for some patients with continued twice-daily use. In clinical studies, Xiidra reduced symptoms of eye dryness at 2 weeks in 2 out of 4 studies, with improvements observed at 6 and 12 weeks in all 4 studies.
#Study Design: Soft contact lens wearers with dryness symptoms at study start (n=40) all received Xiidra twice a day for 12 weeks. Participants were instructed to remove their contact lenses prior to instillation of Xiidra and wait 15 minutes prior to placing the lenses back in their eyes.
Study Limitation: This was a single-center, open label study with no control treatment arm. Data are based on descriptive statistics and should be interpreted with caution. All participants had to have used artificial tears or rewetting drops at least once in the month prior to study start; only 30% of participants had used these eye drops twice per day (Xiidra dosing frequency), while the remaining 70% either had to increase (62%) or decrease (8%) their daily dosing frequency during the study. It is possible that the more frequent use of Xiidra as compared to previous drops could have contributed to the reduction in symptoms in some participants.
Xiidra Savings
Commercially insured? Eligible patients may pay as little as $0 on their first 90-day prescription—and as little as $0 for each refill—with a Xiidra Savings Card.||
Get Started||Offer not valid for patients whose prescriptions are reimbursed by any federal or state healthcare program, including Medicaid, Medicare, TRICARE, or any other federal or state healthcare program. Other restrictions apply. See complete Eligibility Criteria and Terms and Conditions.
What is Xiidra?
Show Less
What is Xiidra?
Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.
Important Safety Information
Do not use Xiidra if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction.
The most common side effects of Xiidra include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation.
To help avoid eye injury or contamination of the solution, do not touch the container tip to your eye or any surface. If you wear contact lenses, remove them before using Xiidra and wait for at least 15 minutes before placing them back in your eyes.
It is not known if Xiidra is safe and effective in children under 17 years of age.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
For additional safety information, click here for Full Prescribing Information and Patient Information and discuss with your doctor.
What is Xiidra?
Show More
What is Xiidra?
Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.
Important Safety Information
Do not use Xiidra if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction.
The most common side effects of Xiidra include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation.
