Helpful Resources | XIIDRA® (lifitegrast ophthalmic solution) 5%

Exciting news for patients! Xiidra has the BEST* insurance coverage for any branded dry eye prescription product across Commercial and Medicare prescription plans!

More Support Along the Way

Hit play to hear from a real patient with chronic dry eye, and then explore the other resources on this page.

*Based on MMIT data from February 2025. Up to 94% of commercial and 70% of Medicare Part D patients may be covered.

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Patient Brochure

Learn about the basics of chronic dry eye, how Xiidra can help, and more.

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How to Use Xiidra

Xiidra is a twice-daily prescription medicine, applied with one drop in each eye. Be sure to familiarize yourself with the instructions.

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Doctor Discussion Guide

Talk to your doctor about chronic dry eye. A few quick questions can help lead a productive conversation about your symptoms and medical history.

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Xiidra FAQ

Have more questions? Get the answers for your most frequently asked questions here.

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Patient Treatment Xpectatiions Video

Learn more about what to expect with using Xiidra.

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How to Use Xiidra

Take Xiidra twice daily as prescribed by your doctor. It helps to set a reminder to apply one drop in each eye, twice a day, approximately 12 hours apart. Be sure not to touch the container tip to your eye or any surface.

Single-Use Containers

Xiidra comes in single-use containers. Each container holds enough medicine to treat both of your eyes for one application. Once the container is opened, it is important that you apply Xiidra right away. Then throw out the container along with any unused solution. Don’t save it for later.

Using Xiidra With Contact Lenses

If you wear contacts, remove them before using Xiidra. Then wait at least 15 minutes before putting them back in.

Possible Side Effects

The most common side effects of Xiidra include:

Eye irritation
Discomfort or blurred vision when the drops are applied to the eyes
An unusual taste sensation

Seek medical care immediately if you get any symptoms of wheezing, difficulty breathing, or swollen tongue. These are not all the possible side effects of Xiidra. Tell your doctor if you have any side effects that bother you.

Tips to consider on your dry eye journey

Set up your space

Adjust work area and computer for comfort.

Limit screen time

Take a 20-second break for every 20 minutes of screen time you spend, and take an occasional break from your devices when possible.

Adjust room humidity

Low humidity can make dry eye disease symptoms worse.

Follow treatment as recommended by your eye doctor

It's important to know that Xiidra can take time to work, and it may take some time for you to see symptom relief.

Xiidra reduced symptoms of eye dryness at 2 weeks in 2 out of 4 clinical studies, with improvements observed at 6 and 12 weeks in all 4 studies.

Dry eye is considered chronic and may be progressive. Be sure to use Xiidra as directed by your doctor—and discuss any questions with them.

Which dry eye symptoms bother you?

(Please select all that apply)

Dry Tired Watery Blurry AchyLike something’s in my eye Itchy Stinging Burning None of these

1/5

How often do you experience these symptoms?

Frequently Sometimes Rarely

Please select at least one option to continue

2/5

How are you currently treating your dry eyes?

Over-the-counter eye drops or artificial tears Xiidra^® Nothing currently Other therapy A prescription treatment (not Xiidra^®)

Please select at least one option to continue

3/5

When do your dry eye symptoms bother you?

(Please select all that apply)

In dry weather When looking at screens for a long time When I wear contact lenses Other

4/5

Are you interested in talking with an eye doctor about a prescription treatment that may provide symptom relief?

Yes No Maybe

Please select at least one option to continue

5/5

Please share a little information about yourself below to get your quiz results and personalized discussion guide.

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See if you qualify for the Xiidra Savings Card or our other savings programs and pay as little as $0.^†

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See if you qualify for the Xiidra Savings Card or our other savings programs and pay as little as $0.^†

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^†Offer not valid for patients whose prescriptions are reimbursed by any federal or state healthcare program, including Medicaid, Medicare, TRICARE, or any other federal or state healthcare program. Other restrictions apply. See complete Eligibility Criteria and Terms and Conditions

What is Xiidra?

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What is Xiidra?

Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.

Important Safety Information

Do not use Xiidra if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction.

The most common side effects of Xiidra include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation.

To help avoid eye injury or contamination of the solution, do not touch the container tip to your eye or any surface. If you wear contact lenses, remove them before using Xiidra and wait for at least 15 minutes before placing them back in your eyes.

It is not known if Xiidra is safe and effective in children under 17 years of age.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For additional safety information, click here for Full Prescribing Information and Patient Information and discuss with your doctor.

What is Xiidra?

What is Xiidra?

Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.

Important Safety Information

Do not use Xiidra if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction.

The most common side effects of Xiidra include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation.

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